Human Biology & BioImaging

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Human Biology & BioImaging



Latest Publications:

Chagin VO, Reinhart B, Becker A, Mortusewicz O, Jost KL, Rapp A, Leonhardt H and Cardoso MC (2019). Processive DNA synthesis is associated with localized decompaction of constitutive heterochromatin at the sites of DNA replication and repair. Nucleus, 10, 231-253. PubMed

Kasper MA, Gerlach M, Schneider AFL, Groneberg C, Ochtrop P, Boldt S, Schumacher D, Helma J, Leonhardt H, Christmann M and Hackenberger C (2019). NHS-modified ethynylphosphonamidates enable the synthesis of configurationally defined protein conjugates. Chembiochem., 2019 Oct 29. [Epub ahead of print] PubMed

See the feature interview in Pharma Technology Focus on drug delivery: "A safer ride: The latest innovation in targeted cancer treatment" by Abi Millar.


Bringing cancer medication safely to its destination

Kasper MA, Stengl A, Ochtrop P, Gerlach M, Stoschek T, Schumacher D, Helma J, Penkert M, Krause E, Leonhardt H and Hackenberger C (2019). Ethynylphosphonamidates for the rapid and cysteine selective generation of efficacious Antibody-Drug-Conjugates. Angew Chem Int Ed Engl., 58, 11631-11636. PubMed

Kasper MA, Glanz M, Stengl A, Penkert M, Klenk S, Sauer T, Schumacher D, Helma J, Krause E, Cardoso MC, Leonhardt H and Hackenberger C (2019). Cysteine-selective phosphonamidate electrophiles for modular protein bioconjugations. Angew Chem Int Ed Engl., 58, 11625-11630. PubMed



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