Publications
Smets M, Link S, Wolf P, Schneider K, Solis V, Ryan J, Meilinger D, Qin W and Leonhardt H (2017). DNMT1 mutations found in HSANIE patients affect interaction with UHRF1 and neuronal differentiation. Hum. Mol. Genet., 26, 1522-1534. PubMed
Becker A, Zhang P, Allmann L, Meilinger D, Bertulat B, Eck D, Hofstaetter M, Bartolomei G, Hottiger M, Schreiber V, Leonhardt H and Cardoso MC (2016). Poly(ADP-ribosyl)ation of methyl CpG binding protein 2 regulates chromatin structure. J Biol Chem., 291, 4873-81. PubMed
Schmidt CS, Bultmann S, Meilinger D, Zacher B, Tresch A, Maier KC, Peter C, Martin DE, Leonhardt H and Spada F (2012). Global DNA Hypomethylation Prevents Consolidation of Differentiation Programs and Allows Reversion to the Embryonic Stem Cell State. PLoS One, 2012 Dec 27, e52629. PubMed
Arand J, Spieler D, Karius T, Branco MR, Meilinger D, Meissner A, Jenuwein T, Xu G, Leonhardt H, Wolf V and Walter J (2012). In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methlytransferases. PLoS Genet, 2012 June; 8: e1002750. PubMed
Casas-Delucchi CS, van Bemmel JG, Haase S, Herce HD, Nowak D, Meilinger D, Stear JH, Leonhardt H and Cardoso MC (2012). Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin. Nucleic Acids Res., 40, 159-69. PubMed
Pichler G, Wolf P, Schmidt CS, Meilinger D, Schneider K, Frauer C, Fellinger K , Rottach A and Leonhardt H (2011). Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways. J. Cell Biochem. Epub 2011 May 19. PubMed
Frauer C, Rottach A, Meilinger D, Bultmann S, Fellinger K, Hasenöder S, Wang M, Qin W, Söding J, Spada F and Leonhardt H (2011). Different Binding Properties and Function of CXXC Zinc Finger Domains in Dnmt1 and Tet1. PLoS ONE, 6(2): e16627. PubMed
Meilinger D, Fellinger K, Bultmann S, Rothbauer U, Bonapace IM, Klinkert WE, Spada F and Leonhardt H (2009). Np95 interacts with de novo DNA methyltransferases Dnmt3a and 3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells. EMBO Reports, 10, 1259-64. PubMed
Schermelleh L, Haemmer A, Spada F, Rösing N, Meilinger D, Rothbauer U, Cardoso MC and Leonhardt H (2007). Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation. Nucleic Acids Res., 35, 4301-12. PubMed