Human Biology & BioImaging

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List of selected recent publications


Solovei I, Kreysing M, Lanctot C, Koesem S, Peichl L, Cremer T, Guck J and Joffe B (2009). Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution. Cell, 137, 356-368. PubMed

Joffe B, Leonhardt H and Solovei I* (2010). Differentiation and large scale spatial organization of the genome. Curr Opin Gen Dev, 20, 562-569. PubMed

Eberhart A, Feodorova Y, Song C, Wanner G, Kiseleva E, Furukawa T, Kimura H, Schotta G, Leonhardt H, Joffe B and Solovei I* (2013). Epigenetics of eu- and heterochromatin in inverted and conventional nuclei from mouse retina. Chromosome Res, 21, 535-554. PubMed

Solovei I, Wang AS, Thanisch K, Schmidt CS, Krebs S, Zwerger M, Cohen TV, Devys D, Foisner R, Peichl L, Herrmann H, Blum H, Engelkamp D, Stewart CL, Leonhardt H and Joffe B (2013). LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation. Cell, 152, 584-598. PubMed 

Song C, Feodorova Y, Guy J, Peichl L, Jost KL, Kimura H, Cardoso MC, Bird A, Leonhardt H, Joffe B and Solovei I* (2014). DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution. Epigenetics & Chromatin, 7, 17. PubMed

Joffe B, Peichl L, Hendrickson A, Leonhardt H and Solovei I* (2014). Diurnality and Nocturnality in Primates: An Analysis from the Rod Photoreceptor Nuclei Perspective. Evol Biol, 41, 1-11. EvolBiol

Solovei I*, Thanisch K and Feodorova Y (2016). How to rule the nucleus: divide et impera. Curr Opin Cell Biol., 40, 47-59. PubMed

Thanisch K, Song C, Engelkamp D, Koch J, Wang A, Hallberg E, Foisner R, Leonhardt H, Stewart CL*, Joffe B and Solovei I* (2017). Nuclear envelope localization of LEMD2 is developmentally dynamic and lamin A/C dependent yet insufficient for heterochromatin tethering. Differentiation, 94, 58-70. PubMed

van de Werken HJ, de Haan JC, Feodorova Y, Bijos D, Weuts A, Theunis K, Holwerda S, Meuleman W, Pagie L, Thanisch K, Kumar P, Leonhardt H, Marynen P, van Steensel B, Voet T, de Laat W, Solovei I* and Joffe B (2017). Small chromosomal regions position themselves autonomously according to their chromatin class. Genome Res., 27, 922-933. PubMed

Falk M, Feodorova Y, Naumova N, Imakaev M, Lajoie BR, Leonhardt H, Joffe B, Dekker J, Fudenberg G*, Solovei I* and Mirny L* (2018). Heterochromatin drives organization of conventional and inverted nuclei. bioRxiv preprint: bioRxiv  


Some methodological papers from our group


Ronneberger O, Baddeley D, Scheipl F, Verveer PJ, Burkhardt H, Cremer C, Fahrmeir L, Cremer T and Joffe B (2008). Spatial quantitative analysis of fluorescently labeled nuclear structures: problems, methods, pitfalls. Chromosome Res, 16, 523-562.  PubMed

Solovei I (2010). Fluorescence in situ hybridization (FISH) on tissue cryosections. In: Methods Mol Biol, vol. 659: 71-82. PubMed

Solovei I* and Cremer M (2010). 3D-FISH on cultured cells combined with immunostaining. In: Methods Mol Biol, vol. 659: 117-126. PubMed

Eberhart A, Kimura H, Leonhardt H, Joffe B and Solovei I* (2012). Reliable detection of epigenetic histone marks and nuclear proteins in tissue cryosections. Chromosome Res, 20, 849-858. PubMed

Feodorova Y, Koch M, Bultmann S, Michalakis S and Solovei I* (2015). Quick and reliable method for retina dissociation and separation of rod photoreceptor perikarya from adult mice. MethodsX, 2, 39-46. PubMed