Human Biology & BioImaging

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Zülske T, Attou A, Groß L, Hörl D, Harz H and Wedemann G (2024). Nucleosome spacing controls chromatin spatial structure and accessibility. Biophys J., 123, 847-857. PubMed

Bachem K, Li X, Ceolin S, Mühling B, Hörl D, Harz H, Leonhardt H, Arnoult L, Weber S, Matarlo B, Prud'homme B and Gompel N (2024). Regulatory evolution tuning pigmentation intensity quantitatively in Drosophila. Sci Adv., 10, eadl2616. PubMed

Palikyras S, Sofiadis K, Stavropoulou A, Danieli-Mackay A, Varamogianni-Mamatsi V, Hörl D, Nasiscionyte S, Zhu Y, Papadionysiou I, Papadakis A, Josipovic N, Zirkel A, O'Connell A, Loughran G, Keane J, Michel A, Wagner W, Beyer A, Harz H, Leonhardt H, Lukinavicius G, Nikolaou C and Papantonis A (2024). Rapid and synchronous chemical induction of replicative-like senescence via a small molecule inhibitor. Aging Cell, 9, e14083. PubMed

Schmacke NA, O'Duill F, Gaidt MM, Szymanska I, Kamper JM, Schmid-Burgk JL, Mädler SC, Mackens-Kiani T, Kozaki T, Chauhan D, Nagl D, Stafford CA, Harz H, Fröhlich AL, Pinci F, Ginhoux F, Beckmann R, Mann M, Leonhardt H and Hornung V (2022). IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network. Immunity, 55, 2271-2284.e7. PubMed

Brandstetter K, Zülske T, Ragoczy T, Hörl D, Guirao-Ortiz M, Steinek C, Barnes T, Stumberger G, Schwach J, Haugen E, Rynes E, Korber P, Stamatoyannopoulos JA, Leonhardt H, Wedemann G and Harz H (2022). Differences in nanoscale organization of regulatory active and inactive human chromatin. Biophys J., 121, 977-990. PubMed

Zhang L, Isselstein M, Köhler J, Eleftheriadis N, Huisjes N, Guirao M, Narducci A, Smit J, Stoffels J, Harz H, Leonhardt H, Herrmann A and Cordes T (2022). Linker Molecules Convert Commercial Fluorophores into Tailored Functional Probes during Bio-labeling. Angew Chem Int Ed Engl., 61, e202112959. PubMed

Schwach J, Kolobynina K, Brandstetter K, Gerlach M, Ochtrop P, Helma J, Hackenberger CPR, Harz H, Cardoso MC, Leonhardt H and Stengl A (2021). Site-Specific Antibody Fragment Conjugates for Reversible Staining in Fluorescence Microscopy. Chembiochem., 22, 1205-1209. PubMed

Le Poul Y, Xin Y, Ling L, Mühling B, Jaenichen R, Hörl D, Bunk D, Harz H, Leonhardt H, Wang Y, Osipova E, Museridze M, Dharmadhikari D, Murphy E, Rohs R, Preibisch S, Prud’homme B and Gompel N (2020). Regulatory encoding of quantitative variation in spatial activity of a Drosophila enhancer. Sci. Adv., 6, eabe2955. PubMed

Cremer M, Brandstetter K, Maiser A, Rao SSP, Schmid VJ, Guirao-Ortiz M, Mitra N, Mamberti S, Klein KN, Gilbert DM, Leonhardt H, Cardoso MC, Lieberman Aiden E, Harz H and Cremer T (2020). Cohesin depleted cells rebuild functional nuclear compartments after endomitosis. Nat Commun., 11, 6146. PubMed

Hörl D, Rojas Rusak F, Preusser F, Tillberg P, Randel N, Chhetri RK, Cardona A, Keller PJ, Harz H, Leonhardt H, Treier M and Preibisch S (2019). BigStitcher: Reconstructing high-resolution image datasets of cleared and expanded samples. Nature Methods,  16, 870-874. PubMed

Chiu HY, Bates JA, Helma J, Engelke H, Harz H, Bein T and Leonhardt H (2018). Nanoparticle Mediated Delivery and Small Molecule Triggered Activation of Proteins in the Nucleus. Nucleus, 9, 530-542. PubMed

Middleton AM, Dal Bosco C, Chlap P, Bensch R, Harz H, Ren F, Bergmann S, Wend S, Weber W, Hayashi KI, Zurbriggen MD, Uhl R, Ronneberger O, Palme K, Fleck C and Dovzhenko A (2018). Data-Driven Modeling of Intracellular Auxin Fluxes Indicates a Dominant Role of the ER in Controlling Nuclear Auxin Uptake. Cell Rep., 22, 3044-3057. PubMed

Feldmann DP, Cheng Y, Kandil R, Xie Y, Mohammadi M, Harz H, Sharma A, Peeler DJ, Moszczynska A, Leonhardt H, Pun SH and Merkel OM (2018). In vitro and in vivo delivery of siRNA via VIPER polymer system to lung cells. J Control Release, 276, 50-58.  PubMed

Ungewiß H, Vielmuth F, Suzuki ST, Maiser A, Harz H, Leonhardt H, Kugelmann D, Schlegel N and Waschke J (2017). Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase. Sci Rep., 7, 6329. PubMed

Natale F, Rapp A, Yu W, Maiser A, Harz H, Scholl A, Grulich S, Anton T, Hörl D, Chen W, Durante M, Taucher-Scholz G, Leonhardt H and Cardoso MC (2017). Identification of the elementary structural units of the DNA damage response. Nat Commun., 8, 15760. PubMed

Schlenker R, Olguín-Contreras LF, Leisegang M, Schnappinger J, Disovic A, Rühland S, Nelson PJ, Leonhardt H, Harz H, Wilde S, Schendel DJ, Uckert W, Willimsky G and Noessner E (2017). Chimeric PD-1:28 receptor upgrades low-avidity T cells and restores effector function of tumor-infiltrating lymphocytes for adoptive cell therapy. Cancer Res., 77, 3577-3590. PubMed

Schueder F, Strauss MT, Hoerl D, Schnitzbauer J, Schlichthaerle T, Strauss S, Yin P, Harz H, Leonhardt H and Jungmann R (2017). Universal Super-Resolution Multiplexing by DNA Exchange. Angew Chem Int Ed Engl., 56, 4052-4055. PubMed

Balaji R, Bielmeier C, Harz H, Bates J, Stadler C, Hildebrand A and Classen AK (2017). Calcium spikes, waves and oscillations in a large, patterned epithelial tissue. Sci Rep., 7, 42786. PubMed

Bielmeier C, Alt S, Weichselberger V, La Fortezza M, Harz H, Jülicher F, Salbreux G and Classen AK (2016). Interface Contractility between Differently Fated Cells Drives Cell Elimination and Cyst Formation. Curr Biol., 26, 563-74. PubMed

Qin W, Wolf P, Liu N, Link S, Smets M, Mastra F, Forné I, Pichler G, Hörl D, Fellinger K, Spada F, Bonapace IM, Imhof A, Harz H and Leonhardt H (2015). DNA methylation requires a DNMT1 ubiquitin interacting motif (UIM) and histone ubiquitination. Cell Res., 25, 911-29. PubMed

Rühland S, Wechselberger A, Spitzweg C, Huss R, Nelson PJ and Harz H (2015). Quantification of in vitro mesenchymal stem cell invasion into tumor spheroids using selective plane illumination microscopy. J Biomed Opt., 20, 040501. PubMed