Human Biology & BioImaging

Breadcrumb Navigation




Mirny LA and Solovei I (2021). Keeping chromatin in the loop(s). Nat Rev Mol Cell Biol., 2021 Jan 27. [Epub ahead of print] PubMed

Frohns F, Frohns A, Kramer J, Meurer K, Rohrer-Bley C, Solovei I, Hicks D, Layer PG and Löbrich M (2020). Differences in the Response to DNA Double-Strand Breaks between Rod Photoreceptors of Rodents, Pigs, and Humans. Cells, 9, e947. PubMed

Feodorova Y, Falk M, Mirny LA and Solovei I (2020). Viewing Nuclear Architecture through the Eyes of Nocturnal Mammals. Trends Cell Biol., 30, 276-289. PubMed

Subramanian K, Weigert M, Borsch O, Petzold H, García-Ulloa A, Myers EW, Ader M, Solovei I and Kreysing M (2019). Rod nuclear architecture determines contrast transmission of the retina and behavioral sensitivity in mice. eLife, 8, e49542. PubMed

Falk M, Feodorova Y, Naumova N, Imakaev M, Lajoie BR, Leonhardt H, Joffe B, Dekker J, Fudenberg G, Solovei I and Mirny LA (2019). Heterochromatin drives compartmentalization of inverted and conventional nuclei. Nature, 570, 395-399. PubMed

van de Werken HJ, de Haan JC, Feodorova Y, Bijos D, Weuts A, Theunis K, Holwerda S, Meuleman W, Pagie L, Thanisch K, Kumar P, Leonhardt H, Marynen P, van Steesel B, Voet T, de Laat W, Solovei I and Joffe B (2017). Small chromosomal regions position themselves autonomously according to their chromatin class. Genome Res., 27, 922-933. PubMed

Thanisch K, Song C, Engelkamp D, Koch J, Wang A, Hallberg E, Foisner R, Leonhardt H, Stewart CL, Joffe B and Solovei I (2017). Nuclear envelope localization of LEMD2 is developmentally dynamic and lamin A/C dependent yet insufficient for heterochromatin tethering. Differentiation, 94, 58-70. PubMed

Solovei I, Thanisch K and Feodorova Y (2016). How to rule the nucleus: divide et impera. Curr Opin Cell Biol., 40, 47-59. PubMed

Feodorova Y, Koch M, Bultmann S, Michalakis S and Solovei I (2015). Quick and reliable method for retina dissociation and separation of rod photoreceptor perikarya from adult mice. MethodsX, 2, 39-46. PubMed

Song C, Feodorova Y, Guy J, Peichl L, Jost KL, Kimura H, Cardoso MC, Bird A, Leonhardt H, Joffe B and Solovei I (2014). DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution. Epigenetics Chromatin, 7, 17. PubMed

Thanisch K, Schneider K, Morbitzer R, Solovei I, Lahaye T, Bultmann S and Leonhardt H (2014). Targeting and tracing of specific DNA sequences with dTALEs in living cells. Nucleic Acids Res., 2014 Apr, 42:e38. PubMed

Mardaryev AN, Gdula MR, Yarker JL, Emelianov VU, Poterlowicz K, Sharov AA, Sharova TY, Scarpa JA, Joffe B, Solovei I, Chambon P, Botchkarev VA and Fessing MY (2014). p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells. Development, 141, 101-11.  

Eberhart A, Feodorova Y, Song C, Wanner G, Kiseleva E, Furukawa T, Kimura H, Schotta G, Leonhardt H, Joffe B and Solovei I (2013). Epigenetics of eu- and heterochromatin in inverted and conventional nuclei from mouse retina.  Chromosome Res., 21, 535-54. PubMed

Joffe B, Peichl L, Hendrickson A, Leonhardt H and Solovei I (2013). Diurnality and Nocturnality in Primates: An Analysis from the Rod Photoreceptor Nuclei Perspective. Evol Biol, 41, 1-11.

Jack AP, Bussemer S, Hahn M, Pünzeler S, Snyder M, Wells M, Csankovszki G, Solovei I, Schotta G and Hake SB (2013). H3K56me3 is a novel, conserved heterochromatic mark that largely but not completely overlaps with H3K9me3 in both regulation and localization. PLoS One, 8, e51765. PubMed

Solovei I, Wang AS, Thanisch K, Schmidt CS, Krebs S, Zwerger M, Cohen TV, Devys D, Foisner R, Peichl L, Herrmann H, Blum H, Engelkamp D, Stewart CL, Leonhardt H and Joffe B (2013). LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation. Cell, 152, 584-598. LMU news, PubMed

Eberhart A, Kimura H, Leonhardt H, Joffe B and Solovei I (2012). Reliable detection of epigenetic histone marks and nuclear proteins in tissue cryosections. Chromosome Res., 20, 849-58. PubMed

Casas-Delucchi CS, Brero A, Rahn H-P, Solovei I, Wutz A, Cremer T, Leonhardt H and Cardoso MC. (2011). Histone acetylation controls the inactive X chromosome replication dynamics. Nat Commun, 2, 222, 1-11. PubMed

Solovei I and Joffe B  (2010). Inverted nuclear architecture and its development during differentiation of mouse rod photoreceptor cells: a new model to study nuclear architecture. Genetika, 46, 1159-1163. PubMed

Joffe B, Leonhardt H and Solovei I (2010). Differentiation and large scale spatial organization of the genome. Curr Opin Genet Dev., 20, 562-569. PubMed

Nemeth A, Conesa A, Santoyo-Lopez J, Medina I, Montaner D, Peterfia B, Solovei I, Cremer T, Dopazo J and Langst G (2010). Initial genomics of the human nucleolus. PLoS Genet, 6:e1000889. PubMed

Peric-Hupkes D, Meuleman W, Pagie L, Bruggeman SW, Solovei I, Brugman W, Gräf S, Flicek P, Kerkhoven RM, van Lohuizen M, Reinders M, Wessels L and van Steensel B (2010). Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation. Mol Cell., 38, 603-613. PubMed

Solovei  I and Cremer M (2010). 3D-FISH on cultured cells combinedwith immunostaining. Methods Mol Biol. 659, 117-26. 

Solovei I (2010). Fluorescence in situ hybridization (FISH) on tissue cryosections. Methods Mol Biol. 659, 71-82. 


Solovei I, Kreysing M, Lanctot C, Koesem S, Peichl L, Cremer T, Guck J and Joffe B (2009). Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution. Cell 137, 356-368. 

Shimi T, Pfleghaar K, Kojima S, Pack CG, Solovei I, Goldman AE, Adam SA, Shumaker DK, Kinjo M, Cremer T and Goldman RD (2008). The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription. Genes Dev 22, 3409-21. PubMed

Yang S, Illner D, Teller K, Solovei I, van Driel R, Joffe B, Cremer T, Eils R and Rohr K (2008). Structural analysis of interphase X-chromatin based on statistical shape theory. Biochim Biophys Acta 1783, 2089-99. PubMed

Solovei I, Pasero P and Visa N (2008). A journey into the nucleus. Conference on Nuclear Structure and Dynamics. EMBO Rep. 9, 228-33.

Rauch J, Knoch TA, Solovei I, Teller K, Stein S, Buiting K, Horsthemke B, Langowski J, Cremer T, Hausmann M and Cremer C (2008). Light optical precision measurements of the active and inactive Prader-Willi syndrome imprinted regions in human cell nuclei. Differentiation, 76, 66-82.

Cremer M, Müller S, Köhler D, Brero A and Solovei I (2007). Cell Preparation and Multicolor FISH in 3D Preserved Cultured Mammalian Cells. CSH Protoc, 2007: pdb prot4723.

Teller K, Solovei I, Buiting K, Horsthemke B and Cremer T (2007). Maintenance of imprinting and nuclear architecture in cycling cells. Proc Natl Acad Sci U S A

Solovei I, Grasser F and Lanctot C (2007). FISH on Histological Sections. CSH Protoc, 2007: pdb prot4729.

Merico V, Barbieri J, Zuccotti M, Joffe B, Cremer T, Redi CA, Solovei I and Garagna S (2007). Epigenomic differentiation in mouse preimplantation nuclei of biparental, parthenote and cloned embryos. Chromosome Res 15, 341-360. 

Walter J, Joffe B, Bolzer A, Albiez H, Benedetti PA, Müller S, Speicher MR, Cremer T, Cremer M, and Solovei I (2006). Towards many colors in FISH on 3D-preserved interphase nuclei. Cytogenet Genome Res. 114, 367-378.

Solovei I, Schermelleh L, Albiez H and Cremer T (2006). Detection of the cell cycle stages in situ in growing cell populations. In Cell Biology Handbook: A Laboratory Manual, 3rd Edition. Vol. 1. J. Celis, editor. Elsevier Academic Press, Amsterdam. 291-299.

Albiez H, Cremer M, Tiberi C, Vecchio L, Schermelleh L, Dittrich S, Kupper K, Joffe B, Thormeyer T, von Hase J, Yang S, Rohr K, Leonhardt H, Solovei I, Cremer C, Fakan S and Cremer T (2006). Chromatin domains and the interchromatin compartment form structurally defined and functionally interacting nuclear networks. Chromosome Res 14, 707-733. 

Cremer T, Cremer M, Dietzel S, Muller S, Solovei I and Fakan S (2006). Chromosome territories--a functional nuclear landscape. Curr Opin Cell Biol. 18, 307-16. 

Bolzer A, Kreth G, Solovei I, Koehler D, Saracoglu K, Fauth C, Muller S, Eils R, Cremer C, Speicher MR and Cremer T (2005). Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes. PLoS Biol. 3, e157. 

Solovei I, Schermelleh L, Düring K, Engelhardt A, Stein S, von Hase J, Cremer C and Cremer T (2004). Differences in centromere positioning of cycling and postmitotic human cell types. Chromosoma 112, 410-423. 

Solovei I, Grandi N, Knoth R, Volk B and Cremer T (2004). Postnatal changes of pericentromeric heterochromatin and nucleoli in postmitotic Purkinje cells during murine cerebellum development. Cytogenet and Genome Res. 105, 302-310.

Juntao G, Köhler D, Solovei I, Cremer T, Eils R, Mattes J (2004). Assessing the similarity of spatial configurations using distance differences and bending energy: Application to chromosomal interphase arrangements in HeLa cell clones. IEEE ISBI 2004, 1400-1403.

Weierich C, Brero A, Stein S, von Hase J, Cremer C, Cremer T and  Solovei I (2003). Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes. Chromosome Res. 11, 485-502. 

Alexandrova O, Solovei I, Cremer T and David CN (2003). Replication labeling patterns and chromosome territories typical of mammalian nuclei are conserved in the early metazoan Hydra. Chromosoma. 112, 190-200. 

Cremer M, Solovei I, Schermelleh L and Cremer T (2003). Chromosomal arrangement during different phases of the cell cylce. In Nature enzyclopedia of the human genome. Macmillan Publishers Ltd, Nature Publishing Group. 451-457.

Rodionov AV, Lukina NA, Galkina SA, Solovei I and Saccone S (2002). Crossing over in chicken oogenesis: cytological and chiasma-based genetic maps of the chicken lampbrush chromosome 1. J Hered, 93, 125-9.

Solovei I, Cavallo A, Schermelleh L, Jaunin F, Scasselati C, Cmarko D, Cremer C, Fakan S and Cremer T (2002). Spatial preservation of nuclear chromatin architecture during three-dimensional fluorescence in situ hybridization (3D-FISH). Exp Cell Res. 276, 10-23.

Solovei I, Walter J, Cremer M, Habermann F, Schermelleh L and Cremer T (2002). FISH on three-dimensionally preserved nuclei. In FISH: a practical approach, chapter 7. B. Beatty, S. Mai, and J. Squire, editors. Oxford University Press, Oxford. 119-157.

Tanabe H, Muller S, Neusser M, von Hase J, Calcagno E, Cremer M, Solovei I, Cremer C and Cremer T (2002). Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates. Proc Natl Acad Sci U S A. 99, 4424-9.

Tanabe H, Habermann FA, Solovei I, Cremer M and Cremer T (2002). Non-random radial arrangements of interphase chromosome territories: evolutionary considerations and functional implications. Mutat Res. 504, 37-45.

Cremer M, von Hase J, Volm T, Brero A, Kreth G, Walter J, Fischer C, Solovei I, Cremer C, and Cremer T. (2001). Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells. Chromosome Res. 9, 541-67.

Habermann FA, Cremer M, Walter J, Kreth G, von Hase J, Bauer K, Wienberg J, Cremer C, Cremer T and Solovei I (2001). Arrangements of macro- and microchromosomes in chicken cells. Chromosome Res. 9, 569-84. 

Teranishi M, Shimada Y, Hori T, Nakabayashi O, Kikuchi T, Macleod T, Pym R, Sheldon B, Solovei I, Macgregor H and Mizuno S (2001). Transcripts of the MHM region on the chicken Z chromosome accumulate as non-coding RNA in the nucleus of female cells adjacent to the DMRT1 locus. Chromosome Res, 9, 147-65.

Schermelleh L, Solovei I, Zink D and Cremer T (2001). Two-color fluorescence labeling of early and mid-to-late replicating chromatin in living cells. Chromosome Res. 9, 77-80.

Solovei I, Kienle D, Little G, Eils R, Savelyeva L, Schwab M, Jäger W, Cremer C and Cremer T (2000). Topology of double minutes (dmins) and homogeneously staining regions (HSRs) in nuclei of human neuroblastoma cell lines. Genes Chromosomes Cancer, 29, 297-308.

Cremer T, Kreth G, Koester H, Fink RH, Heintzmann R, Cremer M, Solovei I, Zink D and Cremer C (2000). Chromosome territories, interchromatin domain compartment, and nuclear matrix: an integrated view of the functional nuclear architecture. Crit Rev Eukaryot Gene Expr, 10, 179-212

Saccone S, Federico C, Solovei I, Croquette MF, Della Valle G and Bernardi G (1999). Identification of the gene-richest bands in human prometaphase chromosomes. Chromosome Res, 7, 379-86.


Solovei IV, Joffe BI, Hori T, Thomson P, Mizuno S and Macgregor HC (1998). Unordered arrangement of chromosomes in the nuclei of chicken spermatozoa. Chromosoma, 107, 184-8.

Solovei I, Ogawa A, Naitor M, Mizuno S and Macgregor H (1998). Specific chromomeres on the chicken W lampbrush chromosome contain specific repetitive DNA sequence families. Chromosome Res, 6, 323-7.

Joffe BI, Solovei IV and Macgregor HC (1998). Ordered arrangement and rearrangement of chromosomes during spermatogenesis in two species of planarians (Plathelminthes). Chromosoma, 107, 173-83.

Ogawa A, Solovei I, Hutchison N, Saitoh Y, Ikeda JE, Macgregor H and Mizuno S (1997). Molecular characterization and cytological mapping of a non-repetitive DNA sequence region from the W chromosome of chicken and its use as a universal probe for sexing carinatae birds. Chromosome Res, 5, 93-101.

Goldberg MW, Solovei I and Allen TD (1997). Nuclear pore complex structure in birds. J Struct Biol, 119, 284-94.

Solovei IV, Joffe BI, Gaginskaya ER and Macgregor HC (1996). Transcription of lampbrush chromosomes of a centromerically localized highly repeated DNA in pigeon (Columba) relates to sequence arrangement. Chromosome Res, 4, 588-603.

Joffe BI, Solovei IV and Macgregor HC (1996). Ends of Chromosomes in Polycelis tenuis (Platyhelminthes) have telomere repeat TTAGGG. Chromosome Res, 4, 323-4.

Hori T, Suzuki Y, Solovei I, Saitoh Y, Hutchison N, Ikeda JE, Macgregor H and Mizuno S (1996). Characterization of DNA sequences constituting the terminal heterochromatin of the chicken Z chromosome. Chromosome Res, 4, 411-26.

Solovei I, Macgregor H and Gaginskaya E (1995). Single stranded nucleic acid binding structures on chicken lampbrush chromosomes. J Cell Sci, 108 ( Pt 4), 1391-6.

Solovei I, Gaginskaya ER and and Macgregor HC (1994). The arrangement and transcription of telomere DNA sequences at the ends of lampbrush chromosomes of birds. Chromosome Res, 2, 460-70.

Solovei I, Gaginskaya E, Hutchison N and Macgregor H (1993). Avian sex chromosomes in the lampbrush form: the ZW lampbrush bivalents from six species of bird. Chromosome Res, 1, 153-66.

Solovei I, Gaginskaya E, Allen T and Macgregor H (1992). A novel structure associated with a lampbrush chromosome in the chicken, Gallus domesticus. J Cell Sci, 101 ( Pt 4), 759-72.

Rodionov AV, Chel’sheva LA, Solovei IV and Miakoshina IuA (1992). [Chiasma distribution in the lampbrush chromosomes of the chicken Gallus gallus domesticus: hot spots of recombination and their possible role in proper dysjunction of homologous chromosomes at the first meiotic division]. Genetika, 28, 151-60.

Chelysheva LA, Solovei IV, Rodionov AV, Iakovlev AF and Gaginskaia ER (1990). [The lampbrush chromosomes of the chicken. Cytological maps of the macrobivalents]. Tsitologiia, 32, 303-16.