Human Biology & BioImaging
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Publications

Gnan S, Flyamer IM, Klein KN, Castelli E, Rapp A, Maiser A, Chen N, Weber P, Enervald E, Cardoso MC, Bickmore WA, Gilbert DM and Buonomo SCB (2021). Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction. Nat Commun., 12, 2910. PubMed

Levone BR, Lenzken SC, Antonaci M, Maiser A, Rapp A, Conte F, Reber S, Mechtersheimer J, Ronchi AE, Mühlemann O, Leonhardt H, Cardoso MC, Ruepp MD and Barabino SML (2021). FUS-dependent liquid-liquid phase separation is important for DNA repair initiation. J Cell Biol., 220, e202008030. PubMed

Rausch C, Weber P, Prorok P, Hörl D, Maiser A, Lehmkuhl A, Chagin V, Casas-Delucchi CS, Leonhardt H and Cardoso MC (2020). Developmental differences in genome replication program and origin activation. Nucleic Acids Res., 48, 12751-12777. PubMed

Cremer M, Brandstetter K, Maiser A, Rao SSP, Schmid VJ, Guirao-Ortiz M, Mitra N, Mamberti S, Klein KN, Gilbert DM, Leonhardt H, Cardoso MC, Lieberman Aiden E, Harz H and Cremer T (2020). Cohesin depleted cells rebuild functional nuclear compartments after endomitosis. Nat Commun., 11, 6146. PubMed

Schmitt S, Tahk S, Lohner A, Hänel G, Maiser A, Hauke M, Patel L, Rothe M, Josenhans C, Leonhardt H, Griffioen M, Deiser K, Fenn NC, Hopfner KP and Subklewe M (2020). Fusion of bacterial flagellin to a dendritic cell-targeting αCD40 antibody construct coupled with viral or leukemia-specific antigens enhances dendritic cell maturation and activates peptide-responsive T cells. Frontiers in Immunology, 11, 602802. PubMed

Maiser A, Dillinger S, Längst G, Schermelleh L, Leonhardt H and Németh A (2020). Super-resolution in situ analysis of active ribosomal DNA chromatin organization in the nucleolus. Sci Rep., 10, 7462. PubMed

Wagner A, Hofmeister O, Rolland SG, Maiser A, Aasumets K, Schmitt S, Schorpp K, Feuchtinger A, Hadian K, Schneider S, Zischka H, Leonhardt H, Conradt B, Gerhold JM and Wolf A (2019). Mitochondrial Alkbh1 localises to mtRNA granules and its knockdown induces mitochondrial UPR in humans and C. elegans. J. Cell Sci., 132, 19. PubMed

Mahamid J, Tegunov D, Maiser A, Arnold J, Leonhardt H, Plitzko JM and Baumeister W (2019). Liquid-crystalline phase transitions in lipid droplets are related to cellular states and specific organelle association. Proc Natl Acad Sci U S A,  116, 16866-16871. PubMed

Reiter K, Polzer H, Krupka C, Maiser A, Vick B, Rothenberg-Thurley M, Metzeler KH, Dörfel D, Salih HR, Jung G, Nößner E, Jeremias I, Hiddemann W, Leonhardt H, Spiekermann K, Subklewe M and Greif PA (2018). Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia. Leukemia, 32, 313-322. PubMed

Rehage N, Davydova E, Conrad C, Behrens G, Maiser A, Stehklein JE, Brenner S, Klein J, Jeridi A, Hoffmann A, Lee E, Dianzani U, Willemsen R, Feederle R, Reiche K, Hackermüller J, Leonhardt H, Sharma S, Niessing D and Heissmeyer V (2018). Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA. Nat Commun, 9, 299. PubMed

Essig K, Hu D, Guimaraes JC, Alterauge D, Edelmann S, Raj T, Kranich J, Behrens G, Heiseke A, Floess S, Klein J, Maiser A, Marschall S, Hrabĕ de Angelis M, Leonhardt H, Calkhoven CF, Noessner E, Brocker T, Huehn J, Krug AB, Zavolan M, Baumjohann D and Heissmeyer V (2017). Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells. Immunity, 47, 1067-1082.e12 PubMed

Andreeva L, Hiller B, Kostrewa D, Lässig C, de Oliveira Mann CC, Jan Drexler D, Maiser A, Gaidt M, Leonhardt H, Hornung V and Hopfner KP (2017). cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders. Nature, 549, 394-398. PubMed

Cremer M, Schmid VJ, Kraus F, Markaki Y, Hellmann I, Maiser A, Leonhardt H, John S, Stamatoyannopoulos J and Cremer T (2017). Initial high-resolution microscopic mapping of active and inactive regulatory sequences proves non-random 3D arrangements in chromatin domain clusters. Epigenetics Chromatin, 10, 39. PubMed

Ungewiß H, Vielmuth F, Suzuki ST, Maiser A, Harz H, Leonhardt H, Kugelmann D, Schlegel N and Waschke J (2017). Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase. Sci Rep., 7, 6329. PubMed

Natale F, Rapp A, Yu W, Maiser A, Harz H, Scholl A, Grulich S, Anton T, Hörl D, Chen W, Durante M, Taucher-Scholz G, Leonhardt H and Cardoso MC (2017). Identification of the elementary structural units of the DNA damage response. Nat Commun., 8, 15760. PubMed

Crevenna AH, Blank B, Maiser A, Emin D, Prescher J, Beck G, Kienzle C, Bartnik K, Habermann B, Pakdel M, Leonhardt H, Lamb DC and von Blume J (2016). Secretory cargo sorting by Ca2+-dependent Cab45 oligomerization at the trans-Golgi network. J Cell Biol., 213, 305-14. PubMed

Chagin VO, Casas-Delucchi CS, Reinhart M, Schermelleh L, Markaki Y, Maiser A, Bolius JJ, Bensimon A, Fillies M, Domaing P, Rozanov YM, Leonhardt H and Cardoso MC (2016). 4D Visualization of replication foci in mammalian cells corresponding to individual replicons. Nat Commun, 7, 11231. PubMed

Hahn M, Dambacher S, Dulev S, Kuznetsova AY, Eck S, Wörz S, Sadic D, Schulte M, Mallm JP, Maiser A, Debs P, von Melchner H, Leonhardt H, Schermelleh L, Rohr K, Rippe K, Storchova Z and Schotta G (2013). Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin. Genes Dev., 27, 859-72. PubMed 

Kaufmann D, Gassen A, Maiser A, Leonhardt H and Janzen CJ (2012). Regulation and spatial organization of PCNA in Trypanosoma brucei. Biochem Biophysic Res Commun, 419, 698-702 PubMed

Cordes T, Maiser A, Steinhauer C, Schermelleh L and Tinnefeld P (2011). Mechanisms and advancement of antifading agents for fluorescence microscopy and single-molecule spectroscopy.  Phys Chem Chem Phys.,  13, 6699-709. PubMed

Wiedemann SM, Mildner SN, Bönisch C, Israel L, Maiser A, Matheisl S, Straub T, Merkl R, Leonhardt H, Kremmer E, Schermelleh E and Hake SB (2010). Identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y. J. Cell Biol. 190, 777-791. PubMed.